From the Makers of PATANOL^® Solution & PATANASE^® Nasal Spray

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WHY AM I AN ALLERGY SUFFERER?

Hundreds or even thousands of ordinary substances can trigger allergic reactions for typical allergy sufferers. These are called "allergens."

Among the most common allergens are:

Plant pollens
Molds
Household dust (dust mites)
Animal dander
Industrial chemicals
Foods
Medicines
Insect stings

For an allergy sufferer, an allergic reaction may occur anywhere in the body. Areas that the reaction usually appears are places where special immune system cells are stationed to fight off invaders that are inhaled, swallowed or come in contact with the body, including:

The skin
The eyes
Lining of the stomach, intestines, nose, sinuses, throat and lungs

Allergies can affect anyone, regardless of age, gender, race or socioeconomic factors. While it's true that allergies are more common in children, they can occur for the first time at any age or, in some cases, recur after many years of remission. Although the exact genetic factors that make one an "allergy sufferer" are not yet understood, the tendency toward allergies, as well as to allergic disease, is linked to heredity.

Regularly scheduled, repeated exposure to small amounts of an allergen can lead to immunity, whereas infrequent and erratic exposure does not confer immunity but increases the likelihood of producing allergen sensitization.

Irregular exposure to allergens can lead to the production of antibodies (called IgE-mediated antibodies). The presence of these antibodies, when exposed to an allergen can lead to an allergic reaction for most allergy sufferers.

Immunotherapy

When an allergist starts a patient on allergy shots, called immunotherapy, the allergen exposure is closely regulated and given on a scheduled basis. Small amounts of allergens are given over a period of time to build up to maintenance doses. This leads to the production of blocking antibodies (called IgG antibodies) and a decrease in the level of allergic or IgE-mediated antibodies. The long-term goal of allergy shots or immunotherapy is, for the allergy sufferer, to live a healthy life without the daily symptoms of severe allergy.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATIONS and USAGE:
PATADAY™ Solution is indicated for the treatment of ocular itching associated with allergic conjunctivitis.

Dosing and Administration: The recommended dose is one drop in each affected eye once a day.

IMPORTANT SAFETY INFORMATION:
PATADAY™ (olopatadine hydrochloride ophthalmic solution) 0.2% should not be used to treat contact lens related irritation. The preservative in PATADAY™ solution, benzalkonium chloride, may be absorbed by soft contact lenses. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling PATADAY™ Solution before they insert their contact lenses. Safety and effectiveness in pediatric patients below the age of 3 have not been established.

Contraindications: PATADAY™ Solution is contraindicated in patients with a hypersensitivity to any components of this product.

Adverse Events: The most common adverse reations to PATADAY™ Solution were cold syndrome and pharyngitis reported at an incidence of approximatedly 10%. Other adverse events included eye pain, blurred vision, sinusitis and headache occuring in 5% or less of the patients.

As with any eye drop, to prevent contaminating the dropper tip and solution, care should be taken not to touch the eyelids or surrounding areas with the dropper tip of the bottle. Keep bottle tightly closed when not in use. Patients should be advised not to wear a contact lens if their eye is red.

Click here for full prescribing information.

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Olopatadine is licensed from KYOWA HAKKO KOGYO CO., LTD. Japan. PATADAY™ (olopatadine hydrochloride ophthalmic solution) 0.2% is a registered trademark of Alcon, Inc. PATADAY™ Solution is available by prescription only.

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